God changes us into a new creation when we become born again, it is His work.
To say that we could lose what God did in us, would be like saying you are more powerful than God, He's the one that transforms us into a new creation. But there are those who think we can untransform ourselves by our mere deeds.
To say that we could lose that is saying we can overpower God, that God is supject to us rather than us being subject to Him.
We cannot undo what God does, it is His power not ours that makes us a new creation. It is His power that keeps us, therefore we have no power to obtain our salvation through our own effort, nor do we have power to maintain our salvation through our own effort.
2 Corinthians 5:16-19
"16 Therefore from now on we recognize no one according to the flesh; even though we have known Christ according to the flesh, yet now we know Him in this way no longer.
17 Therefore if anyone is in Christ, he is a new creature; the old things passed away; behold, new things have come.
18 Now all these things are from God, who reconciled us to Himself through Christ and gave us the ministry of reconciliation,
19 namely, that God was in Christ reconciling the world to Himself, not counting their trespasses against them, and He has committed to us the word of reconciliation."
Ephesians 2:10
"For we are His workmanship, created in Christ Jesus for good works, which God prepared beforehand so that we would walk in them."
What part of "HIS WORKMANSHIP" do we not understand?
All those who think they are working hard to keep what they did not earn, are not resting in the arms of Jesus, but struggling daily to be sure they can do or be enough to please God.
No one can do enough to please God, that's why Christ had to die to cover our sins, it took the shedding of blood of the only Righteous Perfect Lamb of God to do this. And we think our measly little feeble efforts and attempts to be good would be more than what Christ did? How incredibly silly is that!
Let's call it what it is to think we can keep what we did not earn, it is pride, we like to think we did something to help God. Many like to think they have power over their own destiny, they don't want to let go of their own power over this life or over eternity.
True faith is trusting Christ for salvation and for everything after that. We like to make salvation complicated so that we can maintain some of the control. Until we see our helplessness before Him, we cannot fully trust Him.